Strategic · Insightful · Knowledge-based · Actionable Research Advisory

Building world-class research ecosystems for health systems and academia

Sikara Consultancy partners with community hospitals, health systems, academic institutions, and innovators to build the research infrastructure, partnerships, and workforce that drive innovation and improve patient outcomes.

25+
Years of research leadership
4
Major health systems led
29+
Peer-reviewed publications
3
Strategic growth phases
Who we are

Research excellence is not reserved
for large academic centers

Sikara exists to elevate the research enterprise across health systems, clinics, and academic institutions — building world-class ecosystems that accelerate innovation, improve patient outcomes, and advance scientific discovery.

Our vision is rooted in strengthening the research infrastructure of organizations so they can operate with excellence, agility, and long-term sustainability — delivering highly specialized, actionable, and scalable solutions that traditionally only large institutions can afford.

Empower
Build high-performing research ecosystems that translate scientific ambition into operational reality and deliver meaningful impact for patients and communities.
Connect
Forge stronger site–sponsor and cross-sector partnerships — bridging health systems with Pharma, Technology, and Life Sciences innovators to integrate scalable, real-world solutions.
Elevate
Cultivate a skilled, confident, and future-ready research workforce through transformative education, training, and academic-level learning experiences.
What we do

End-to-end advisory across the research continuum

From infrastructure development to workforce training, Sikara provides expert advisory services tailored to the scale and mission of your organization.

🏗️
Research Infrastructure Development
  • Research readiness gap analysis
  • Establish R&D units and research offices
  • SOP, policy, and governance frameworks
  • Research prioritization and review committees
  • Executive and leader buy-in strategy
  • Risk management systems for research
🔬
Clinical Trial Support
  • Site activation readiness
  • Regulatory submissions (IRB/IEC)
  • CTMS review and workflow design
  • Phase I–IV trial execution support
  • Patient recruitment strategies
  • Clinical trial staffing plans
📄
Investigator-Initiated Research
  • Protocol writing support
  • Feasibility assessments
  • Learner research assessment (UME, GME)
  • Grant preparation and funding strategy
  • IIR program design
💾
Data Infrastructure & Digital Research
  • Data governance frameworks
  • Research data warehouse review
  • EDC and CTMS evaluation
  • Real-world evidence strategy
  • Statistical support planning
💰
Grants & Funding Strategy
  • Grant review and readiness
  • Federal grant lifecycle management
  • OMB compliance and Single Audit prep
  • Funding pipeline planning
  • Philanthropy partnership strategy
🎓
Workforce Training & Capacity Building
  • Clinical trial operations training
  • Research methodology workshops
  • Leadership training for research teams
  • College-level course design
  • SOP bundles and digital toolkits
Client engagements

Trusted by innovators across the research ecosystem

Sikara brings strategic advisory expertise to a diverse portfolio of clients — from healthcare technology companies and real-world evidence platforms to academic research programs — each at a different stage of growth and with a distinct research mission.

🏥
Highlander Health & Pedestal Health
Real-World Evidence · Health System Innovation

Highlander Health is a Dallas-based platform launched in 2024 that modernizes clinical research and patient care through learning labs, investment, and philanthropy — bringing together providers, regulators, academics, and life sciences partners to advance next-generation evidence generation. Pedestal Health, a portfolio company, delivers regulatory-grade real-world evidence for life sciences, with depth in hepatology, dermatology, and gastroenterology through its TARGET-DERM and related registries.

Sikara's role
Health system engagement strategy — connecting Highlander Health and Pedestal Health with the right health system partners to expand real-world evidence generation and clinical research collaboration.
🤖
Brim Analytics
AI · Clinical Data · Chart Abstraction

Brim Analytics is a Nashville-based healthcare technology company founded at Vanderbilt University Medical Center and backed by $3.9M in ARPA-H funding. Brim's AI-guided chart abstraction platform transforms unstructured clinical notes into structured, research-ready data — combining large language models with human-in-the-loop review to accelerate clinical research, registry management, and trial enrollment at academic medical centers and health systems nationwide.

Sikara's role
Strategic positioning and health system and academic engagement — helping Brim navigate and build relationships with health systems and academic medical centers, and positioning the platform within the clinical research and real-world evidence market.
🎓
RESTORE Program
San Diego State University · Community Health Research

The RESTORE program at San Diego State University is a community-based health research initiative focused on recovery, resilience, and health equity — bringing together academic researchers, community partners, and health systems to study and address the social and behavioral determinants of health in underserved populations. SDSU is an R1 research university and federally designated Hispanic-Serving Institution with a deep commitment to community-engaged, translational health research.

Sikara's role
Operationalizing the RESTORE program — including developing validated survey instruments, building and configuring REDCap data capture systems, defining data variables and collection protocols, and facilitating stakeholder and community facilitator sessions to ensure rigorous, community-centered research implementation.
VN
Vani Nilakantan
PhD · Founder & Principal
Clinical Research Research Strategy Health Systems Kidney Transplant Real-World Evidence IIR Leadership Federal Grants AI in Health
Founder Profile

25+ years shaping research at the nation's largest health systems

Vani Nilakantan brings a rare combination of academic scientist, institutional executive, and cross-sector strategist. Beginning with a research faculty career at the Medical College of Wisconsin, she has led research programs at four major health systems — building programs, forging partnerships, and translating scientific ambition into operational excellence at scale. She is an ad-hoc reviewer for Kidney International, British Journal of Urology, PPAR Research, and Free Radicals in Biology and Medicine, with 29+ peer-reviewed publications and NIH- and AHA-funded research.

2026
Sikara Consultancy LLC
Founder & Principal Consultant
Founded to deliver specialized, scalable research advisory services to health systems, clinics, and academic institutions that cannot access traditional CRO resources.
2019–2025
CommonSpirit Health Research Institute
System Vice President, Research
Provided vision and strategy for one of the largest health systems in the U.S. — 162 hospitals, 40 teaching facilities, research across 13 states. Accountable executive and authorized official; partnered with industry, life science companies, and academic organizations. Led PCORI, PAS cardiovascular and neurological, and AI-driven RWE collaborations.
~2015–2019
Allina Health
Executive Head of Research
Led clinical and basic research for a large integrated health system in Minneapolis. Served as authorized organizational representative, set strategic direction, and reorganized the research structure for the system.
~2010–2015
Aurora Health Care / Advocate Health
Director, IIR & Sponsored Programs Office
Oversaw basic science, pre-clinical, translational, and clinical research at Aurora Research Institute. Researched racial disparities in organ transplantation and novel biomarkers in cardiac and acute kidney injury.
~2000–2010
Medical College of Wisconsin (MCW)
Assistant Professor of Surgery & Research Faculty
Led active research program in ischemic acute kidney injury and renal protection in kidney transplantation. Research funded by NIH and AHA. Published 29+ peer-reviewed papers and contributed to 3 multi-investigator grants.
Our differentiators

Why organizations choose Sikara

01
Cross-functional expertise
Deep expertise spanning research operations, data governance, regulatory compliance, grant management, and workforce development — rare to find in a single advisory partner.
02
Right-sized for your organization
Tailored solutions for small and mid-size organizations that large CROs price out of reach. Scalable from startup research programs to enterprise-level research units.
03
Vendor-neutral & evidence-based
No platform relationships, no preferred vendors. Every recommendation is grounded in evidence and your institutional context — not a product partnership incentive.
04
Proven at scale
Built and led research programs at CommonSpirit Health, Allina Health, Aurora/Advocate Health, and MCW — four of the country's largest and most complex research environments.
05
Cross-sector bridge
Experienced in aligning health systems with pharma, life sciences, and technology partners — creating durable partnerships that advance both research excellence and operational innovation.
06
Flexible engagement models
Short-term hourly consulting, project-based contracts, and long-term retainer partnerships — structured to meet your operational and financial realities at every stage of growth.
Business model

A three-phase growth strategy

Sikara is built for long-term scale — starting with foundational engagements and growing into a nationally and internationally recognized research advisory practice.

Phase 1

Launch

Year 1

Foundational services with known and local clients. Establish consulting frameworks, develop digital products (SOPs, templates, toolkits), and build an early portfolio of health system and academic institution engagements.

Phase 2

Expand

Years 2–3

National expansion with a portfolio of health systems and academic institutions. Add retainer partnerships, grow the team, and establish Sikara as the go-to advisory for community hospital research programs and IIR strategy.

Phase 3

Scale

Year 3+

International scale through digital products, global partnerships, and virtual training programs. Position Sikara as a trusted global partner for research ecosystem development across health systems, academic institutions, and life sciences organizations.

Who we serve

Our target markets

Sikara serves a broad range of organizations across the research and health innovation ecosystem — from single-site clinics to large integrated health systems.

Community-based hospitals Small & mid-size health systems Academic medical centers Medical colleges & universities Public health institutions Research networks Nonprofits & NGOs in health research Small & mid-size clinics Life science & pharma companies Health technology companies
Get started

Ready to build your research ecosystem?

Whether you're launching a first research program or scaling an existing one, Sikara brings the expertise, strategy, and partnership to get you there.

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